负责人：雷群英
秘书：史薇
电话：021-54237792
邮箱：sw@fudan.edu.cn
二级学科：
1.人体解剖学和组织胚胎学
研究方向：
(1)生殖细胞发育异常与不孕不育的表观遗传调控;（陈红）
(2)基于人脑组织库的衰老和神经精神疾病机制研究;（刘琼）
(3)组织再生及肿瘤发生的分子基础;（王作云）
(4)脑高级功能的神经解剖学环路研究;（袁向山）
专业领域主要专家：陈红、刘琼；王作云；袁向山等。
2. 免疫学
研究方向：
(1)免疫生物治疗及转化研究；
(2)肿瘤免疫及自身免疫的分子与细胞基础；
(3)基于免疫细胞的免疫调控及机理研究；
(4)区域免疫调节及机制研究；
(5)感染性疾病发病的免疫学机制；
(6)病原体免疫逃逸的分子机制。
本专业领域主要专家：储以微、何睿、王继扬、吕鸣芳、张伟娟、严大鹏、徐薇、魏园园、林玉丽等教授。
3.病原生物学
研究方向：
(1)乙型肝炎病毒和丙型肝炎病毒分子生物学与分子免疫学;
(2)微生物基因组结构和功能的研究;
(3)微生物与细胞相互作用及机制的研究;
(4)微生物感染的新型诊断和治疗策略的研究;
(5)针对各类病原体的抗体免疫应答反应; B淋巴细胞中抗体生成的分子机制;
(6)合成免疫学;
(7)病毒慢性感染和免疫调节；新型抗病毒靶标药物
(8)病毒感染与体液免疫;
(9)肠道微生态与代谢性疾病;
(10)功能性治愈慢性乙肝病毒感染的基础研究
(11)病毒和抗病毒免疫中蛋白的结构和功能
本专业领域内主要专家：闻玉梅（院士）、袁正宏、谢幼华、程训佳、吴健、高谦、王乔、张荣、应天雷、陈捷亮、李建华、吕亮东、王勇翔、赵宝玉等教授。
4. 病理学与病理生理学 (病理学)
研究方向：
(1)肿瘤病理
本专业领域内主要专家：刘秀萍、王漱阳、刘颖、刘国元、章平肇、李飞、王宇翔等
(2)慢性病病理（包括肾病病理与肝病病理）
本专业领域内主要专家：刘秀萍、吴慧娟、刘学光、徐延勇等
5. 病理学与病理生理学 (病理生理学)：
研究方向：
(1)心血管重构的分子机制及干预；
(2)血管再生修复的调控机制及干预；
(3)干细胞分化心血管细胞的分子机制及应用；
(4)脂质代谢紊乱相关疾病病理生理学。
本专业领域内主要专家：孟丹，陈思锋，钱睿哲，周平，赵猛，李晓波等。
6.法医学
研究方向：
(1)法医病理学：复杂死因的机制解析与鉴识
(2)法医毒物学：药毒物检测方法开发及其毒理机制解析
(3)法医物证学 ：体液鉴定、亲权鉴定
本专业领域内主要专家：陈龙，沈忆文，李立亮，谢建辉，姜宴等
7. 医学信息学
研究方向：医学人工智能
本专业领域内主要专家：宋志坚教授，王满宁教授
8. 医学系统生物学
研究方向：生物化学与分子生物学
(1)甲基化相关酶的分子机制研究
(2)基因表达调控，表观遗传修饰在疾病包括血液病，肿瘤以及神经退行性疾病发生发展中的作用
(3)前沿RNA技术与肿瘤免疫治疗
本专业领域内主要专家：汪振天，蓝贤江，璩良
研究方向：生物信息学
(1)胚胎发育与疾病的系统生物学
(2)单细胞组学的算法开发
本专业领域内主要专家：徐一驰
9. 药理学
研究方向：
(1)药物成瘾分子和神经机制、学习记忆的环路和分子机制、记忆障碍的发病机制；
(2)神经精神药理学、睡眠与失眠的分子机制、开发镇静催眠药物；
(3)靶向神经系统的脂质体药物设计与体内过程研究；
(4)靶向神经疾病的小分子筛选与溶酶体稳态的调控机制；
(5)神经胶质瘤表观发病机制以及基因药物治疗；
(6)临床药理学：神经胶质细胞的治疗药物靶点；
本专业领域内主要专家：马兰（院士）、黄志力、曲卫敏、占昌友、王菲菲、刘星、魏晓丽、李洋、束敏峰、丁凤菲等教授/研究员。
Basic Medical Sciences
1.Human Anatomy and Histo-Embryology
Major Research Projects:
(1) Epigenetic mechanism in germ cell development and infertility;
(2) Mechanisms of aging and neuropsychiatric disorders based on human brain bank;
(3) Molecular basis of tissue regeneration and tumorigenesis;
(4) Neuroanatomical circuit of higher brain functions;
Experts in this Field: Hong Chen, Qiong Liu, Zuoyun Wang, Xiangshan Yuan, et al.
2. Immunology
Major Research Projects:
(1) Immunobiotherapy and translational research;
(2) Molecular and cellular basis of tumor immunity and autoimmunity;
(3) Immune regulation and mechanisms of immune cells;
(4) Immune regulation and mechanisms of regional immunity;
(5) Immune mechanisms involved in pathogenesis of infectious diseases;
(6) The molecular mechanisms of the immune evasion of pathogens.
Experts in this Field: Prof. Chu Yiwei, Prof. He Rui, Prof. Wang Jiyang, Prof. Lv Mingfang, Prof. Zhang Weijuan, Prof. Yan Dapeng, Prof. Xu Wei, Prof. Wei Yuanyuan, Prof. Lin Yuli, etc.
3.Medical Microbiology and Medical Parasitology
Major Research Projects:
(1) Molecular Biology and Immunology of HBV, HCV;
(2) Genomic Structure and Related Functions of Microorganisms;
(3) Microorganisms-Host Interactions
(4) Novel Diagnostics and Therapeutic Agents for Microbial Infections; (5). Antibody Immune Response against Various Pathogens; Molecular (6). Mechanism underlying Antibody Maturation in B Lymphocytes;
Synthetic Immunology;
(7) Chronic Viral Infection and Immune Modulation; Novel Antiviral Targets and Drug Discovery
(8) Virus infection and humoral immune response;
(9) Gut microbiota and pathogenesis of metabolic diseases
(10) Basic research on functional cure of chronic hepatitis B virus infection
(11) Structure and function of proteins in viruses and antiviral immunity
Experts in this Field: Prof. Wen Yumei (Academician), Prof. Yuan Zhenghong, Prof. Xie Youhua, Prof. Chen Xunjia, Prof. Gao Qian, Prof. Wu Jian, Prof. Wang Qiao, Prof. Zhang Rong, Prof. Ying Tianlei, Prof. Chen Jieliang, Prof. Li Jianhua, Prof. Lyu Liangdong, Prof. Wang Yongxiang, Prof. Zhao Baoyu.
4. Pathology and Pathophysiology (Pathology)
Main research orientations:
(1) Tumor Pathology
Main experts: Profs. Xiuping Liu, Shuyang Wang, Ying Liu, Pingzhao Zhang, Fei Li, Yuxiang Wang
(2) Nephropathy and Hepatopathy Pathology
Main experts: Profs. Xiuping Liu, Huijuan Wu, Xueguang Liu, Yanyong Xu
5. Pathology and Pathophysiology (Pathophysiology):
Major Research Projects:
(1) the molecular mechanism and intervention of cardiovascular remodeling；
(2) the regulation mechanism and intervention of vascular regeneration and repair；
(3) the molecular mechanism and application of stem cell differentiation into cardiovascular cells；
(4) pathophysiology of lipid metabolism disorders related diseases.
Experts in this Field: Dan Meng，Sifeng Chen, Ruizhe Qian，Ping Zhou, Meng Zhao, Xiaobo Li
6. Forensic Science
Major Research Projects:
(1) Forensic Pathology: mechanism and forensic appraisal of complicated causes of death
(2) Forensic Toxicology: Drug detection method development and its toxicological mechanisms
(3) Forensic Biology: body fluid identification, paternity identification
Experts in this Field: Chen Long, Shen Yiwen, Li Liliang, Xie Jianhui, Jiang Yan，etc.
7.Medical Informatics
Main research orientations: Artificial Intelligence in Medicine
Experts in this Field: Prof. Song Zhijian，Prof. Wang Manning
8. System Biology for Medicine
Secondary Subjects: Biochemistry and Molecular Biology
Main research orientations:
(1) Molecular Mechanisms of methyltransferases
(2) The role of gene expression regulation and epigenetic modifications in diseases
(3) Cutting-edge RNA technology and tumor immunotherapy
Experts in this Field：Prof. Wang Zhentian, Prof.Lan Xianjiang, Prof.Qu Liang
Secondary Subjects: Bioinformatics
Main research orientations:
(1) systems biology of embryogenesis and diseases
(2) Computational methods in single-cell genomics
Experts in this Field：Prof. Xu Yichi
9. Pharmacology
Major Research Projects:
(1) Molecular and neurocircuits of drug addiction, learning and memory, memory disorders；
(2) Neuropsychopharmacology, molecular mechanisms of sleep and insomnia, development of sedative and hypnotic drugs;
(3) Development and in vivo delivery mechanisms of liposomal formulations for CNS diseases targeting;
(4) Compound screen and mechanisms of lysosome homeostasis；
(5) Epigenetic mechanisms of glioma pathogenesis and gene therapy;
(6) Explorations of therapeutic drugs and targets in neuroglia cells;
Experts in this Field: Prof. Ma Lan (Academician), Prof. Huang Zhili, Prof. Qu Weimin, Prof. Zhan Changyou, Prof. Wang Feifei, Prof. Liu Xing, Wei Xiaoli, Li Yang, Shu Minfeng, Ding Fengfei.
